Promega has recently released its HaloTag® Protein Purification System for easier purification of recombinant proteins.
The purification system delivers soluble, functional recombinant target proteins at higher yield and purity. Promega claims the system outperforms the most commonly used protein tags like His(6)Tag, GST, and MBP.
The HaloTag Protein Purification System is said to be ideal for researchers working with difficult-to-express proteins.
The HaloTag protein is designed to be structurally compatible with fusion protein partners. It delivers enhanced protein expression in multiple systems, higher protein yield and purity.
The HaloTag Protein Purification System enables the study of protein function in both a biochemical and cellular environment using one genetic construct.
The HaloTag technology is based on a unique protein tag which has been engineered from a bacterial dehalogenase to covalently attach to a set of synthetic ligands, such as fluorescent dyes, for cellular imaging applications or to resin and magnetic beads for protein interaction analysis applications.
For further information, see the HaloTag Protein Purification online resources.